| Sample
Papers |
| |
Q.1
In corn there are 10 chromosomes per set
and the species is diploid. A karyotype
was performed from the endosperm cells grown
in tissue culture in a medium containing
colchicine. What is the total number of
chromosomes in an endosperm cell after the
first round of cell divisions?
| (a) 5 |
| (b) 14 |
| (c) 15 |
| (d) 30 |
|
Q.2
Three of the four eukaryotic rRNAs are synthesized
from a single transcription unit consisting
of the rDNA. Which one of the following
does NOT belong to this group?
| (a) 5.8S |
| (b) 5S |
| (c) 18S |
| (d) 28S |
|
Q.3
When ß-[32 P]-ATP is incubated
in an eukaryotic cell extract that is capable
of transcription and RNA processing where
does the label appear in the m-RNA?
| (a) Every phosphate
group of the m RNA is labelled |
| (b) Only the 5-end of
the m RNA is labelled provided the
first base is A |
| (c) Only the 3-end of
the m-RNA is labelled provided the
last base is A |
| (d) The label does not
appear at all in m-RNA |
|
Q.4
Which particle converts
cholesterol to cholesterol esters?
| (a) LDL |
| (b) Chylomicrons |
| (c) VLDL |
| (d) HDL |
|
Q.5
A patient presents with
lethargy and a 10-fold increase in plasma
ammonia and glutamine levels due to a defect
in the urea cycle. The build-up of what
other metabolite in the plasma is consistent
with a defect in ornithine transcarbamoylase
and not carbamoyl phosphate synthetase I?
| (a) Urea |
| (b) Arginine |
| (c) Ornithine |
| (d) Citrulline |
|
Q.6
Tay-Sachs Disease, characterized
by intralysosomal accumulation of the GM2
ganglioside, results from a deficiency in
| (a) Sphingomyelinase. |
| (b) Galactocerebrosidase. |
| (c) Glucocerebrosidase. |
| (d) Hexosaminidase A. |
|
Q.7
Which of the following assays is currently
being used for the detection of Helicobacter
pylori?
| (a) Agglutination |
| (b) Complement fixation |
| (c) Enzyme-linked immunosorbent
assay |
| (d) Immunodiffusion |
|
Q.8
An individual was found to be heterolo-gous
for IgG1 allotypes 3 and 12.
The different possible IgG1 antibodies
produced by this individual will never have
| (a) Two H chains of allotype 12 |
| (b) Two L chains of either Κ
or Λ |
| (c) Two H chains of allotype 3 |
| (d) Two H chains, one of allotype
3 and one of allotype 12 |
|
Q.9
The resting membrane potential
| (a) Occurs only in nerve and muscle
cells |
| (b) Is the same in all cells. |
| (c) Is oriented so that the cell's
interior is positive with respect
to the extracellular fluid. |
| (d) Requires the separation of most
of the cell's charged particles. |
|
Q.10
Which of the following is
NOT part of Koch's postulates?
| (a) The microorganism is never found
in healthy animals. |
| (b) The microorganisms is always
found in diseased animals. |
| (c) The microorganism must cause
disease in healthy animals. |
| (d) The microorganism must secrete
a toxin in culture. |
|
| |